I recommend watching it full screen... and then watching again a few times to catch all of little details and get the full fracked up psycho chick effect...
... kinda reminds me of my girlfriend actually. Huh.
This is one of the funniest, most inspirational videos I have ever watched. Randy Pausch passed away on Friday and if you haven't seen this yet, it is worth the time.
I've watched the first 30 minutes so far Awryt... He was an awesome speaker. Love it so far, but work summons me (yes, a lock, a pally, and a priest are all sitting at my desk clicking on the portal)